Naser A. ElSawy, Department of Laboratory Medicine, Faculty of Applied Medical Sciences, Umm Al-Qura University, Saudi Arabia; Department of Anatomy & Embryology, Faculty of Medicine, Zagazig University, Egypt.

Abdullah G.Alkushi, Department of Anatomy, Faculty of Medicine, Umm Al-Qura University, Saudi Arabia

Amal Almattry, Department of Anatomy & Embryology, Faculty of Medicine, Zagazig University, Egypt

Hataba A.A, Department of Chemistry, Faculty of Science, Zagazig University, Egypt.

Abstract
Toxoplasma gondii (T. gondii) is found worldwide in many species, including carnivorous and herbivorous mammals and birds. The definitive host of this parasite has been shown to be cats, which have been associated with the transmission of the parasite in every population investigated. Serum samples were examined for antibodies to T. gondii, and the analysis for toxoplasma specific antibodies IgG, and IgM were completed within one day in the lab. The prevalence of T. gondii was 47.7% in female patients and 41.6% in male patients. From 225 patients with positive antibodies IgG Abs was detected in 113 women and 88 male and IgM was detected in 13 women and 11 male. There was a highly significant correlation between the (18>40years age group and Toxoplasma infection in this population. Most of the study group were nulliparous with seropositive for IgG and IgM Abs to T.gondii. The high rate of abortion (30.2%) was determined with seropositive IgG and seropositive IgM., IgG Abs were observed in cases with a history of recurrent pregnancy loss while IgM detected with women who had a history of previous abortion. T. gondii is one of the widest spread protozoal parasites infecting abroad spectrum of vertebrates. Toxoplasmosis can cause detrimental effects on anyone who contracts the disease. Thus, it is very important to practice the prevention of the disease so that treatment does not need to be employed.

Keywords
Toxoplasma gondii, stillbirth, prenatal mortality, pregnancy, congenital anomalies

Cite this paper
Naser A. ElSawy, Abdullah G.Alkushi, Amal Almattry, Hataba A.A, Prevalence of Toxoplasma infection in pregnant women and their infants in Makkah Hospitals , SCIREA Journal of Clinical Medicine. Volume 1, Issue 1, October 2016 | PP. 110-126.

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